Combined product image

Harness the synergy between Nature & Medicine.
BOOST your immune system with NATURE'S POWER.* *coupled with proper diet and exercise.

HEALTHMAX CARE MANGOSTEEN PLUS 8 BERRIES

is a unique combination of Mangosteen with 8 Berries including:

Mangosteen

Mangosteen

Acerola Berry

Acerola Berry

Acai Berry

Acai Berries

Wolfberry

Wolfberry

Bilberry

Bilberry

Raspberry

Raspberry

Cranberry

Cranberry

Hawthorn Berry

Hawthorn Berry

Grapeseed

Grapeseed

These ingredients are rich in anthocyanins, which are chemical compounds produced by plants and are found in especially rich amounts in pigmented fruits such as berries.
Anthocyanins, when ingested, bring about a myriad of effects that are beneficial to health.

ANTI-OXIDANT, ANTI-INFLAMMATORY
& IMMUNITY-BOOSTING EFFECTS

OXIDATIVE STRESS

Normal Cell

Mangosteen is known to contain rich amounts of xanthones, which promote immune function and modulate inflammatory processes.

Specifically, studies have shown that consumption of xanthone-rich mangosteen were associated with decreasing CRP concentration compared to placebo.1

Diagram showing the proposed mechanisms of anthocyanins' anti-inflammatory and anti-dyslipidemic effects

Summary of proposed mechanisms of anthocyanins' anti-inflammatory and anti-dyslipidemic effects.5

Oxidative stress is an important risk factor that negatively impacts a patient’s immune status. Antioxidants combat the effect of free radicals and promote health by preventing cell damage.

Anthocyanins and polyphenols found in berries contain rich amounts of antioxidants that address oxidative stress and prevent inflammatory processes.2,3

Graph showing changes in mean (SD) concentrations of the serum cytokines IL-1a, IL-1b, and IL-2

The anti-inflammatory activities of anthocyanins result from attenuation of pro-inflammatory cytokines including TNF-α, IL-1β, IL-6 and COX-2.

Anthocyanins and xanthones combined have both been demonstrated (in vivo and in vitro) to alter the humoral system and improve immune function through specific pathways.1,4 Bioactive compounds in berries have been shown to increase subpopulations of T-cells.4 On the other hand, B-cells were enhanced in terms of their activity rather than their numbers.4

GASTROINTESTINAL HEALTH

Illustration of gastrointestinal health

Consumption of specific types of berries is also associated with the growth and proliferation of beneficial bacteria in the gut. It is proposed that the antioxidant and anti-inflammatory benefits associated with berries derive from their impact on altering the gut microbiota.

Consumption of raspberries as well as other berries have been shown to specifically increase the count of Bifidobacterium, Lactobacillus and Bacteroidetes subspecies in the gut.3 Such effects account for the positive effects of berries in the immune system.

CARDIOMETABOLIC EFFECTS

Illustration of cardiometabolic effects

By virtue of their anti-inflammatory effects, anthocyanins impact the process of atherosclerosis, thereby mitigating risks for cardiovascular diseases. They are known to promote vascular permeability, decrease endothelial dysfunction and prevent platelet aggregation.2 Furthermore, anthocyanins are associated with lipid-lowering effects, resulting from lower rate of oxidation of atherogenic lipoproteins, as demonstrated in animal studies.2

Additionally, abscisic acid found in high doses in bilberries are also shown to have antidiabetic properties. This compound has been demonstrated to upregulate receptors for PPAR-γ, thereby exerting similar effects as thiazolidinediones.5 A high dietary intake of anthocyanins were associated with decreased insulin resistance. Ingestion of bilberry extract containing high levels of abscisic acid were noted to help regulate post-prandial insulin and glucose levels.5

Appropriate medical management is vital to effectively addressing health problems such as infections and chronic cardiometabolic diseases including hypertension, diabetes and high blood cholesterol levels.

Healthmax Care Mangosteen Plus 8 Berries offers safe adjunctive solutions that work hand-in-hand with medical therapy to help boost the functioning of different bodily systems.

Harness the synergy between Nature & Medicine.
BOOST your immune system with NATURE'S POWER.* *coupled with proper diet and exercise.

Healthmax Care Mangosteen +8 Berries

REFERENCES:

1. TANG YP, et al. J Med Food. 2009;12(4):755-763.

2. Zafra-Stone S., et al. Mol Nutr Food Res. 2007;51(6):675-683.

3. Pap N., et al. Current Opinion in Food Science 2021, 42:167-186

4. Vahapoglu B., et al. Molecules. 2021;27:108.

5. Vaneková Z, Rollinger JM. Front Pharmacol. 2022;13:909914